tag:blogger.com,1999:blog-11326364.post3862508411160836909..comments2024-03-27T03:58:43.402-04:00Comments on <center>CasesBlog - Medical and Health Blog</center>: Tiotropium (Spiriva) Treatment in Chronic Obstructive Pulmonary Disease (COPD)Unknownnoreply@blogger.comBlogger3125tag:blogger.com,1999:blog-11326364.post-39378888407051618612009-08-25T18:56:14.724-04:002009-08-25T18:56:14.724-04:00All studies not focused on cardiac disease have si...All studies not focused on cardiac disease have similar exclusion criteria... :)<br /><br />You want as few confounding variables as possible. This is how the studies are done. It's not real life. This is a controlled environment where you answer a focused question.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-11326364.post-41918666938820876702009-08-25T18:52:19.904-04:002009-08-25T18:52:19.904-04:00I agree with the above comment.NEJM exclusion cite...I agree with the above comment.NEJM exclusion citeria included "the presence of a coexisting illness that could preclude participation in the study"....hmm, I wonder how many people with any cardiac conditions were excluded from the study....It seems like they cherry picked the patients who were most likely not to have any cardiac complications.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-11326364.post-25326025621844098652008-10-13T19:57:00.000-04:002008-10-13T19:57:00.000-04:00Did you get a good sense of the NEJM exclusion cri...Did you get a good sense of the NEJM exclusion criteria for the study? I saw a pretty vague description suggesting any patients that weren't suitable for the study were excluded. If these excluded patients were more likely to have cardiac complications, then perhaps the JAMA study does have a basis.Anonymousnoreply@blogger.com