Botox Injections for Treatment of Diabetic Gastroparesis

A 75 year-old female with diabetic gastroparesis is admitted to the hospital with generalized weakness and N/V for 2 days.

She is not able to tolerate metoclopromide (Reglan).

The GI consultant recommends botulinum toxin (Botox) injections of the pylorus.


Figure 1. Stomach filled with food (left); Botulinum toxin was injected in a 4-quadrant fashion in the pylorus (right).

What is the effect of the procedure on the patient's symptoms?

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