Attending rounds: What is SAPHO syndrome?

SAPHO syndrome includes a variety of inflammatory bone disorders that may be associated with skin changes. SAPHO stands for Synovitis-Acne-Pustulosis-Hyperostosis Osteomyelitis.

An entity initially known as Chronic Recurrent Multifocal Osteomyelitis (CRMO) was first described in 1972. The term SAPHO was coined in 1987.

Treatment is with NSAIDs, steroids, methotrexate or Enbrel.

References:
Round 7: Synovitis-Acne-Pustulosis-Hyperostosis osteomyelitis syndrome (SAPHO). Johns Hopkins University School of Medicine.
SAPHO syndrome, from Wikipedia, the free encyclopedia.