Clinical Case: How to Diagnose Common Variable Immunodeficiency (CVID)?

A 65-year-old female has a history of frequent UTIs for the last year. Serum immunoglobulins showed low levels of IgG 515 mg/dL (reference range 700 to 1600), IgM 30 (reference range 40 to 230), IgA 50 (reference range 70 to 400).

What is the reason for the low levels of immunoglobulins?


Five immunoglobulin classes (mind map)

What is the diagnostic work-up for CVID?

What treatment options would you suggest?

Read the rest of the case here: How to Diagnose Common Variable Immunodeficiency (CVID)? from AllergyCases.org.