Lp-PLA2 activity and mass each show continuous associations with risk of coronary heart disease, similar in magnitude to that with non-HDL cholesterol or systolic blood pressure.
Lipoprotein structure (chylomicron). Image source: Wikipedia, GNU Free Documentation License.
Lipoprotein-associated phospholipase A2 and risk of coronary disease, stroke, and mortality: collaborative analysis of 32 prospective studies. The Lancet, Volume 375, Issue 9725, Pages 1536 - 1544, 1 May 2010.