Here are my suggestions for some of the top articles in medicine in June 2012:Risky Music-Listening Behavior Associated with Health-Risk Behavior: alcohol, drugs and unsafe sex (study) http://goo.gl/eoUfL
Study: Couples get health benefits simply from sleeping in the same bed - WSJ http://goo.gl/PBlPJ
Love's initial romantic phase lasts anywhere from 18 months to 3 years, experts say, then it ends - WSJ http://goo.gl/2x1mS
5 Minute Medicine Video Series by Internal Medicine at McMaster University http://bit.ly/KidaPU
Aspiring to Make MDR-TB Nevermore: Delamanid for Multi-drug Resistant Pulmonary Tuberculosis - NEJM http://goo.gl/b7rQ8
The risks and benefits of social media for cardiologists - theheart dot org interview with @doctorwes http://goo.gl/TUfxj
Radiation from 2-3 head CTs in children triple the risk for brain tumors (5-10 CTs triple risk for leukemia) http://goo.gl/xs2ZH - Source: Radiation exposure from CT scans in childhood and subsequent risk of leukaemia and brain tumours: a retrospective cohort study - The Lancet http://goo.gl/teqnX
Inhibiting Hedgehog Pathway in Basal-Cell Cancer: Vismodegib is effective but 50% stop treatment due to adverse events http://goo.gl/966X5
Small-molecule inhibitor of the hedgehog pathway Vismodegib showed 58% response rate in advanced basal-cell cancer http://goo.gl/sJfm1
Another therapeutic option for Multidrug-Resistant TB: Delamanid nitro-dihydro-imidazooxazole inhibits mycolic acid http://goo.gl/zUhYY
Hospital mortality is complex and should be used cautiously in evaluating quality of care. Last 10 years marked by diminishing returns, with growth in costs far outpacing reductions in inpatient mortality http://goo.gl/T16W3
Churchill had a doctor's approval for "medicating with a minimum 250 cc alcohol at meal times" - “This is to certify,” the doctor writes — this in the midst of Prohibition — “that the postaccident convalescence of the Hon. Winston S. Churchill necessitates the use of alcoholic spirits especially at meal times.” The quantity, the doctor continues, is “naturally indefinite,” but the “minimum requirements would be 250 cubic centimeters,” or just over 8 ounces. Archives in NYT http://goo.gl/Yc9cr
The articles were selected from my Twitter and Google Reader streams. Please feel free to send suggestions for articles to clinicalcases@gmail.com and you will receive acknowledgement in the next edition of this publication.