From NHS Choices YouTube channel: Rosacea is a common but poorly understood long-term skin condition that mainly affects the face. It most commonly affects fair-skinned people from northern Europe and is estimated to affect up to 1 in 10 people. In this video, an expert explains what rosacea is, the symptoms to look out for and the various treatments.
Cathelicidin dysfunction may be a central factor in the pathogenesis of several cutaneous diseases, including rosacea.
Cathelicidins are antimicrobial peptides (AMPs) that protect the skin through 2 pathways:
- antimicrobial activity
- cytokine release, inflammation, angiogenesis, and reepithelialization