Botox Injections for Treatment of Diabetic Gastroparesis

A 75 year-old female with diabetic gastroparesis is admitted to the hospital with generalized weakness and N/V for 2 days.

She is not able to tolerate metoclopromide (Reglan).

The GI consultant recommends botulinum toxin (Botox) injections of the pylorus.

Figure 1. Stomach filled with food (left); Botulinum toxin was injected in a 4-quadrant fashion in the pylorus (right).

What is the effect of the procedure on the patient's symptoms?

Read more in Botulinum Toxin Injections for Treatment of Diabetic Gastroparesis.


  1. "My pylorus is wrinkle free!"

    Ok, sorry.

  2. Pylorus relaxation to help with gastric empting.

  3. My 25 year old daughter had this done. It has helped for 4 weeks but Im afraid its losing strength. She does joke and say she has the pylorus of an 18 hear old...